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How a Fish's Immune System Works

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How a Fish's Immune System Works


All fish have an immune system to fight diseases, although the system is by no means as advanced as the ones found in mammals. The system breaks down into two main parts: protection from physical invasion and internal pathogen handling.


Physical protection comes in the form of scales and the layers of dermis and epidermis. These provide defense against physical injury and disease organisms in the environment, which is further improved by a mucus covering that contains bactericides and fungicides. This mucus membrane is constantly renewed. It helps slough off debris and discourages parasites from attaching themselves to the fish.


Pathogens can still enter the fish’s body, either through physical injury or the digestive tract. Although the digestive system has active enzymes and a very pathogen-unfriendly pH level, diseases can sometimes survive. Stress can also be a problem if it causes the gut to seize up — anaerobic fermentation and active enzymes can attack the gut wall and weaken it enough to allow diseases to enter.


The efficiency of a fish’s immune system is affected by its environment. Colder water slows down the system, so infected fishes tend to exhibit “fever symptoms” and head for warmer areas. Colder water may or may not affect the infection: if it does not slow down the pathogens as well as the immune system, death is inevitable.

What is Osmoregulation?


Fishes have some general immunities provided by products in their blood: the antiviral chemical interferon and C-reactive protein immediately attack bacteria and viruses.


As soon as a pathogen is detected, the fish’s body coordinates efforts to resist: firstly, the entry point is sealed off to correct any osmoregulatory problems and hamper the foreign body’s progression. Histamines and other products are produced by damaged cells at the entry point to cause inflammation and make the blood cells close up. Fibrinogen (a blood protein) and clotting factors create a barrier of fibrin to build a physical barrier at the same time. White blood cells are attracted to the same area and pick up the foreign bodies, taking them away to the spleen and kidney for handling.


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A type of slime that is made up of certain salts, cells, or leukocytes


Something that is capable of producing disease


The outside layer of the skin


The skin; also referred to as the corium


Any substance or item that the body of an animal would regard as strange or unwanted; a foreign disease or virus in the body (toxin, etc.)


a) living in an environment lacking free oxygen b) pertaining to an organism with the ability to live in an environment lacking free oxygen.

What Are GloFish?

digestive tract

The whole system involved in digestion from mouth to anus

Source: Internet

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How a Fish's Immune System Works Breed Characteristics

Adaptability starsEnergy Level starsShedding Level stars
Affection Level starsGrooming starSocial Needs stars
Child Friendly starsHealth Issues starsStranger Friendly stars
Dog Friendly starsIntelligence stars
  1. Adaptability stars
  2. Affection Level stars
  3. Child Friendly stars
  4. Dog Friendly stars
  5. Energy Level stars
  6. Grooming star
  7. Health Issues stars
  8. Intelligence stars
  9. Shedding Level stars
  10. Social Needs stars
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